Human Matrin 3 (MATR3) ELISA Kit

Matrin 3 (MATR3) is a nuclear matrix protein that functions as an RNA-binding scaffold involved in pre-mRNA splicing, transcript stability, and nuclear retention of hyper-edited RNAs. Mutations in the MATR3 gene are clinically linked to amyotrophic lateral sclerosis (ALS), distal myopathy with vocal cord weakness, and frontotemporal dementia, making accurate quantification valuable for neurodegeneration, neuromuscular, and RNA biology studies. The microplate-based protocol supports quantitative measurement across tissue homogenates and cell lysates, with reagents provided ready-to-use for standard laboratory incubation and wash steps. Store kit components refrigerated and protect the substrate solution from light to preserve detection performance. This Assay Genie ELISA provides a reproducible approach for monitoring MATR3 expression changes in disease models and comparing human samples without significant cross-reactivity to non-human homologs.