Human Mast/stem cell growth factor receptor Kit (KIT) ELISA Kit

A Sandwich ELISA Kit from Assay Genie designed for the quantitative detection of Human Mast/stem cell growth factor receptor Kit (KIT), also known by synonyms including Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PBT, CD117, and SCFR. The kit is reactive with human serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

Performance characteristics include a detection range of 3.12-200ng/mL and a sensitivity of 1.2ng/mL. Intra-assay CV is 5.7% and inter-assay CV is 9.7%. The kit shows specificity for natural and recombinant human Mast/stem cell growth factor receptor Kit. Recovery in serum averages 102% (range 96-108%) and in plasma averages 104% (range 98-110%).

KIT is a tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and melanogenesis. The associated UniProt accession is P10721 and the research area is Signal Transduction. For research use only.