Human MARK4 ELISA Kit (HUFI03501)

MARK4 (Microtubule Affinity Regulating Kinase 4) is a serine/threonine kinase that regulates microtubule dynamics, neuronal polarity, and mitotic progression in dividing cells. The Assay Genie MARK4 ELISA Kit enables quantitative in vitro measurement of this kinase, supporting neuroscience and oncology research programs focused on tau phosphorylation, neurodegenerative pathways, and tumor cell signaling.

The kit employs a colorimetric readout on a standard microplate reader, with reagents supplied for 96 determinations per run. The workflow accommodates high-throughput screening of cell culture samples and tissue lysates, supporting studies of MARK4 abundance in glioblastoma, epithelial cancers, and neural tissue models. Reagents integrate with common laboratory protocols in kinase biology, neuropharmacology, and cancer signaling research.

Research applications include profiling Alzheimer's-related kinase activity, characterizing MARK4 dysregulation in CNS tumors, and examining the kinase's role in cell polarity and division. The assay accommodates samples from adherent and suspension cell culture systems, supporting both targeted hypothesis testing and broader biomarker discovery efforts. Intended for research use only, the kit provides a reproducible tool for laboratories investigating microtubule-associated kinase function in human disease models.