Human Mannosidase Alpha Class 2B Member 1 (MAN2B1) ELISA Kit

Mannosidase alpha class 2B member 1 (MAN2B1) is a lysosomal hydrolase that cleaves alpha-linked mannose residues from N-linked glycoproteins during glycoprotein catabolism. Mutations in the MAN2B1 gene cause alpha-mannosidosis, a recessively inherited lysosomal storage disorder marked by progressive intellectual disability, skeletal abnormalities, immune deficiency, and sensorineural hearing loss. The Assay Genie MAN2B1 immunoassay kit provides a quantitative enzyme-linked method for measuring MAN2B1 protein in human biofluid and tissue homogenate specimens. Investigators working on lysosomal storage disease pathophysiology, biomarker discovery, and therapeutic monitoring for alpha-mannosidosis use this microplate-format kit as a research tool. Each kit is supplied as a complete reagent set intended for research use only in laboratory settings, supporting reproducible quantitation of MAN2B1 across patient-derived sample cohorts.