Human Mannose Associated Serine Protease 2 (MASP2) ELISA Kit

The MASP2 protein is a 19 kDa serine protease that operates within the lectin pathway of the complement cascade. It circulates in complex with mannose-binding lectin (MBL) and ficolins, where it autoactivates upon pattern recognition to cleave complement components C4 and C2. Dysregulated MASP2 activity has been associated with conditions ranging from ischemic reperfusion injury to certain autoimmune presentations, making it a meaningful analyte in immunology and complement research laboratories.

This quantitative immunoassay from Assay Genie is configured for human serum-type and plasma-type specimens along with other sample matrices and is intended for research use only. The kit is supplied as a complete set of reagents for 96 individual determinations, with all microtitre plate components, standards, and detection reagents included to support endpoint absorbance measurement on standard plate readers. Researchers typically apply this assay when probing lectin pathway activation status, screening patient cohorts for circulating MASP2 concentration differences, or supporting studies of complement-mediated disease mechanisms such as infection, glomerulonephritis, and transplant injury.

Storage recommendation: keep unopened kits refrigerated and protect from light. Allow all reagents to equilibrate to room temperature before use, and avoid repeated freeze-thaw cycles of reconstituted components to preserve activity and assay reproducibility.