Human Mannose Associated Serine Protease 1 (MASP1) ELISA Kit

The MASP1 protein is a critical serine protease that initiates the lectin pathway of complement activation, working in conjunction with mannose-binding lectin to recognize pathogenic carbohydrate patterns on microbial surfaces. Quantitative measurement of circulating MASP1 supports research into innate immunity, complement-related disorders, and developmental syndromes such as 3MC syndrome, where MASP1 gene mutations have been clinically implicated.

This colorimetric immunoassay from Assay Genie provides laboratories with a quantitative tool for measuring MASP1 in human specimens, enabling investigations into lectin pathway activity across immunology, infectious disease, and inflammation studies. The kit format supports 96 assays per plate, accommodating moderate-throughput experimental workflows in academic and translational research environments.

Common research applications include studies of complement activation in autoimmune conditions, monitoring innate immune responses during infection, characterizing patient cohorts with suspected MASP1 deficiency, and exploring the role of MASP1 in coagulation cross-talk with downstream complement components. The assay is intended for in vitro research use only and is appropriate for laboratories investigating the MASP1/MASP2 serine protease family within the lectin activation cascade.

Store the reagents refrigerated to preserve stability through the stated shelf life, protecting capture antibodies and enzymatic components from degradation between experimental runs.