Human MAD2L1 ELISA Kit (HUFI03544)

MAD2L1 (Mitotic Arrest Deficient 2 Like 1) is a core component of the mitotic spindle assembly checkpoint, a surveillance mechanism that delays anaphase until every kinetochore is properly attached to spindle microtubules. This Assay Genie ELISA kit enables quantitative measurement of MAD2L1 protein in human research samples, supporting investigations into chromosome segregation fidelity, aneuploidy, and the molecular defects that drive chromosomal instability in tumor cells.

The kit uses a colorimetric readout on a pre-coated microplate, with standards and detection reagents supplied for generating a calibration curve. Researchers studying cell division, DNA damage response pathways, and cancer biology — particularly the contribution of mitotic checkpoint failure to tumor progression and the efficacy of antimitotic agents — can use this kit to monitor MAD2L1 expression across experimental conditions.

Each kit ships with the antibody-coated plate, biotinylated detection antibody, standard diluent, wash buffer, and TMB substrate. Reagents should be stored at 4°C; consult the enclosed manual for full handling instructions. For research use only.