Human Lysyl oxidase homolog 4 (LOXL4) ELISA Kit

Designed for the accurate detection of Lysyl oxidase homolog 4 (LOXL4) levels in human biological samples, this Sandwich ELISA Kit from Assay Genie is intended for research use only. The assay is reactive with human samples and has been validated for serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

Performance specifications include a detection range of 0.78-50ng/mL and a sensitivity of 0.427ng/mL. Precision is reported as an Intra CV of 6.2% and an Inter CV of 8.9%. Linearity was assessed in serum, EDTA plasma, and heparin plasma at dilutions from 1:2 to 1:16, and recovery averaged 103% for serum (range 97-109%) and 105% for plasma (range 99-111%). The kit is specific for natural and recombinant human LOXL4.

LOXL4 is a secreted extracellular-space enzyme belonging to the lysyl oxidase family and may modulate the formation of a collagenous extracellular matrix. It has been implicated in extracellular matrix remodeling and studied in the context of fibrosis, cancer, and cardiovascular disorders. The kit targets UniProt entry Q96JB6, with synonyms including Lysyl oxidase-like protein 4, Lysyl oxidase-related protein C, and LOXC.