Human LYL1 (Protein lyl-1) ELISA KIT (HUFI05100)

LYL1 (Lymphoblastic Leukemia 1) encodes a class A basic helix-loop-helix transcription factor critical for hematopoietic stem cell self-renewal and T-cell lineage commitment. Dysregulation through chromosomal translocation, most notably t(7;19)(q35;p13) which juxtaposes LYL1 with the TCRβ locus, contributes to T-cell acute lymphoblastic leukemia (T-ALL), making this protein a target of interest in translational oncology and hematology research. This quantitative immunoassay from Assay Genie enables researchers to measure endogenous LYL1 protein levels, supporting investigations into leukemogenesis, immune cell development, and stem cell biology. Each kit supplies all reagents required for the microplate workflow along with detailed protocol documentation and a standard curve for interpolation. Reconstituted standards should be stored frozen at -20 °C in single-use aliquots to limit freeze-thaw cycles, and the streptavidin-HRP conjugate should be protected from light to preserve enzymatic activity. The capture antibody is human-specific, with no significant cross-reactivity observed with the closely related bHLH family members TAL1 and TAL2. Applications include oncology research, leukemia biomarker studies, and hematopoietic stem cell investigations. For research use only; not intended for diagnostic or clinical procedures.