Human LTC4S/Leukotriene C4 synthase ELISA Kit

From Assay Genie, this sandwich ELISA kit uses a double-antibody format with colorimetric detection to quantify human Leukotriene C4 Synthase (LTC4S) in serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. LTC4S is an enzyme involved in the biosynthesis of leukotrienes, lipid mediators with potent inflammatory effects, and its dysregulation has been associated with various inflammatory conditions, making it a valuable biomarker for research into these diseases.

The kit delivers a sensitivity of 46.875 pg/mL across an assay range of 78.125–5000 pg/mL. Reported linearity values are 88–101% (1:2), 93–100% (1:4), and 90–97% (1:8) for serum; 86–97%, 82–98%, and 90–101% for EDTA plasma; and 83–97%, 81–96%, and 81–94% for heparin plasma. Average recovery is 95% for serum (range 90–103%), 99% for EDTA plasma (range 90–104%), and 98% for heparin plasma (range 91–104%).

Storage is at 2–8°C for 12 months. The associated UniProt entry is Q16873, and the kit is positioned within the metabolism research area for studies of LTC4S in inflammation and related disorders.