Human Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) ELISA Kit

This quantitative immunoassay from Assay Genie enables researchers to measure LDL receptor adaptor protein 1 levels in human samples, supplied as a complete kit with 96 assays per plate. LDLRAP1, also referred to as ARH, functions as the cytoplasmic bridge that couples the LDL receptor to clathrin-mediated endocytosis, and loss-of-function variants in this gene cause autosomal recessive hypercholesterolemia, making it a target of interest in lipid metabolism and cardiovascular disease research.

Configured for tissue homogenate samples, the assay produces a colorimetric readout on a standard microplate reader, so no specialized instrumentation beyond what is already present in most research labs is required. Each kit ships with the pre-coated plate, detection reagents, and recombinant standard needed to quantify the analyte across a dilution series.

Typical applications include profiling LDLRAP1 expression in hepatic and extrahepatic tissues, characterizing patient-derived material from individuals with familial hypercholesterolemia, and investigating receptor-mediated endocytosis in cholesterol homeostasis studies.