Human LMNA (Lamin-A) ELISA Kit (HUFI05107)

Lamin-A, encoded by the LMNA gene, is a structural component of the nuclear lamina involved in chromatin organization, DNA repair, and the mechanical integrity of the nucleus. The Human LMNA (Lamin-A) ELISA Kit from Assay Genie is a quantitative immunoassay built for research laboratories studying this protein and its associated laminopathies. Aberrant Lamin-A expression and processing is implicated in Hutchinson-Gilford Progeria Syndrome, Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, and dilated cardiomyopathy, making reliable quantitation valuable for disease-mechanism studies, biomarker discovery, and drug-screening workflows. The kit is configured for 96 Assays and ships with pre-coated plate strips, recombinant Lamin-A standards, biotinylated detection antibody, and streptavidin-HRP conjugate. Quantitation relies on an absorbance readout on a standard microplate reader. Reagents should be refrigerated upon arrival; consult the product manual for component-specific storage conditions. Intended for research use only, the assay also supports investigations of progerin processing, nuclear morphology, and genotype-phenotype correlations in patient-derived cell lines.