Human LIPT1 (Lipoyltransferase 1, mitochondrial) ELISA KIT (HUFI05105)

Researchers investigating mitochondrial lipoic acid metabolism can use this Assay Genie ELISA kit to quantify human LIPT1 (Lipoyltransferase 1, mitochondrial) levels in experimental samples. LIPT1 is a mitochondrial enzyme that catalyzes the transfer of lipoyl groups from the lipoic acid salvage pathway onto 2-oxoacid dehydrogenase multienzyme complexes, including pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase, supporting energy production through the TCA cycle. Loss-of-function mutations in LIPT1 are associated with LIPT1 deficiency, a rare inborn error of metabolism characterized by impaired lipoyl cofactor recycling, lactic acidosis, and early-onset mitochondrial dysfunction, which is why the protein is of growing interest in metabolic disease research. The kit is supplied as a complete set of reagents configured for 96 Assays and is validated for in vitro research use only, fitting applications in mitochondrial biology, characterization of the lipoylation pathway, and studies of cellular metabolism in patient-derived or model system samples.