Human Leukotriene A4 Hydrolase (LTA4H) ELISA Kit

Quantifying a bifunctional zinc metalloenzyme central to eicosanoid biosynthesis, this Assay Genie ELISA targets human Leukotriene A4 Hydrolase (LTA4H), the enzyme that converts leukotriene A4 into the pro-inflammatory lipid mediator leukotriene B4 (LTB4). At approximately 69 kDa, LTA4H also carries aminopeptidase activity on a separate catalytic site, making it relevant to dual-function enzyme regulation studies and drug-target screening. Researchers tracking neutrophil chemotaxis, chronic inflammation, and lipid-mediator signaling rely on this colorimetric microplate assay to measure LTA4H protein levels across human sample types, including tissue homogenates and additional biofluid matrices. Translational applications extend to asthma, atherosclerosis, and selected cancers where LTA4H expression has been linked to disease progression.