Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) ELISA Kit

Targeting the inhibitory immune receptor LILRB4, also known as ILT3, LIR5, and CD85k, this quantitative ELISA kit from Assay Genie supports research into immune tolerance, antigen-presenting cell biology, and tumor immune evasion. LILRB4 is expressed on monocytes, dendritic cells, and tolerogenic myeloid populations, where its engagement of HLA class I ligands modulates dendritic cell maturation and T cell activation. Antibody-mediated blockade of LILRB4 is being investigated in acute myeloid leukemia, where the receptor has been described as a marker of leukemic stem cells and a candidate immunotherapy target.

The kit measures human LILRB4 in tissue homogenates, cell lysates, and other sample types using a paired-antibody assay format with an enzyme-based absorbance readout detected on a standard microplate reader. Researchers studying transplantation tolerance, autoimmune inflammation, and tumor microenvironment immunoregulation commonly use this reagent alongside flow cytometry and Western blot methods to cross-validate expression findings at the protein level. Each kit contains reagents supplied for 96 individual assays and is intended for research use only, not for diagnostic procedures.