Human LCMT1 (Leucine carboxyl methyltransferase 1) ELISA Kit (HUFI03470)

Enabling quantitative measurement of Leucine carboxyl methyltransferase 1 (LCMT1) in human samples, this ELISA Kit from Assay Genie provides a complete research solution for studying the methyltransferase that carboxyl-methylates protein phosphatase 2A (PP2A). LCMT1 catalyzes methylation of PP2A's catalytic C-terminal leucine residue, a modification that governs PP2A holoenzyme assembly, substrate selectivity, and activity toward phosphoproteins in cell-cycle, apoptosis, and tau-phosphorylation pathways. Altered LCMT1 expression has been reported in Alzheimer's disease, multiple cancers, and cellular methylation disorders, supporting its relevance as a research biomarker.

The kit supplies reagents for 96 Assays and is intended for research use only. It is validated for measuring human LCMT1 across a range of standard research sample preparations. Each box contains pre-coated microplate wells, recombinant protein standard, detection antibody, buffers, and substrate solution for plate-reader readout. Reagents are quality-controlled at the lot level and shipped refrigerated to preserve detection antibody activity.