Human LARP1 ELISA Kit (HUFI03648)

An enzyme-linked immunosorbent assay kit from Assay Genie enables quantitative detection of human LARP1, a conserved RNA-binding protein that regulates mRNA stability and cap-dependent translation through the mTOR signaling cascade. Researchers in molecular biology, cancer biology, and ribonomics apply LARP1 measurements to investigate post-transcriptional gene control, ribosomal biogenesis, and tumor cell proliferation.

Configured as a 96 Assays plate-based colorimetric format for in vitro research use only, the kit provides the reagents, standards, and buffers needed to profile LARP1 expression across human research specimens. Each kit supports multiple experimental replicates in cell culture models, primary tissue extracts, and clinical research samples, allowing comparative analysis of LARP1 abundance under different signaling, pharmacological, and stress conditions.

LARP1 contains an N-terminal La motif and adjacent RNA recognition motif that together bind the 5' terminal oligopyrimidine (5'TOP) motif found in mRNAs encoding ribosomal proteins and translation factors, positioning LARP1 as a central regulator of growth-controlled protein synthesis. Direct mTOR-mediated phosphorylation of LARP1 modulates its RNA-binding activity, making LARP1 abundance a useful readout for translational reprogramming in cancer metabolism, immune cell signaling, and cellular stress responses.