Human Laminin subunit alpha-1 (LAMA1) ELISA Kit

Designed for the quantitative measurement of human Laminin subunit alpha-1 (LAMA1), this Sandwich ELISA kit from Assay Genie is a research-grade immunoassay for use with human samples, including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

Reported performance characteristics include a detection range of 0.312-20 ng/mL, sensitivity of 0.12 ng/mL, intra-assay CV of 5.3%, and inter-assay CV of 8.0%. Recovery values averaged 97% (range 91-103%) in serum and 99% (range 93-105%) in plasma. The assay is specific for natural and recombinant human Laminin subunit alpha-1, corresponding to UniProt accession P25391.

Laminin subunit alpha-1 is a subunit of the laminin family of extracellular matrix glycoproteins, which contribute to cell adhesion, migration, and organization during embryonic development by interacting with other extracellular matrix components. Dysregulation of LAMA1 has been linked to cancer, muscular dystrophy, and kidney diseases, supporting its use as a biomarker in related research.