Human LAIR1 PharmaGenie ELISA Kit (SBRS0819)

Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1, also known as CD305) is an ITIM-bearing inhibitory receptor broadly expressed across immune cell populations, including NK cells, T and B lymphocytes, monocytes, and dendritic cells, where it engages collagen and collagen-domain containing ligands to negatively regulate cellular activation. The Assay Genie Human LAIR1 PharmaGenie ELISA Kit delivers quantitative measurement of LAIR1 in human research samples through a matched-antibody pair capture architecture with an absorbance-based readout.

Processing 96 assays per plate, the kit provides throughput for cohort comparisons, dose-response experiments, and multi-condition screening panels. Validated for use with cell culture supernatants, plasma-based workflows, and serum-based biofluid studies, the workflow accommodates both cell-based in vitro studies and ex vivo profiling. Plates are processed on standard laboratory microplate readers, fitting easily into established immunology and biomarker research pipelines.

Investigators apply this kit to study immune checkpoint biology, tumor microenvironment immunosuppression, chronic inflammatory disease mechanisms, and regulation of innate effector function. The assay supports studies of how collagen-binding inhibitory receptors shape immune responses in autoimmunity, oncology, and infectious disease research, where LAIR1 expression and shedding serve as informative biomarkers of immune cell regulation.