Human Kruppel Like Factor 4, Gut (KLF4) ELISA Kit

The KLF4 protein quantified by this kit is a zinc-finger transcription factor encoded on chromosome 9q31.2 and originally cloned from intestinal epithelium, where it drives terminal differentiation of goblet cells and maintains epithelial barrier integrity. Assay Genie's microplate-based assay is widely applied in colorectal cancer research, inflammatory bowel disease studies, and stem cell reprogramming workflows, since KLF4 is one of the four Yamanaka factors (OCT4, SOX2, KLF4, c-MYC) used to generate induced pluripotent stem cells.

Researchers commonly use this kit to measure KLF4 protein levels in colon tumor lysates and matched normal mucosa, as KLF4 acts as a tumor suppressor that is frequently lost or silenced in gastrointestinal malignancies and can inhibit Wnt/beta-catenin signaling. The kit is supplied as a complete pack with pre-coated microplate, standards, and detection antibody; reconstituted reagents should be stored at 4 degrees C short term or aliquoted and frozen at -20 degrees C for longer stability. For research use only in in vitro laboratory studies.