Human Klotho Beta (KLb) ELISA Kit

Researchers investigating aging, metabolic disease, and renal pathophysiology rely on this Assay Genie ELISA kit to quantify soluble β-Klotho in human specimens. β-Klotho operates as a critical co-receptor that partners with FGFR1c, FGFR2c, FGFR3c, and FGFR4 isoforms to mediate FGF19 and FGF21 endocrine signaling, regulating bile acid synthesis, fatty acid oxidation, and glucose homeostasis. This quantitative immunoassay supports clinical biomarker work in type 2 diabetes, chronic kidney disease, non-alcoholic fatty liver disease, and longevity studies where diminished circulating β-Klotho concentrations mark renal tubular dysfunction and metabolic imbalance. Sufficient reagents for 96 individual sample determinations arrive ready-to-use with pre-coated microplate wells, biotinylated detection antibody, and streptavidin-HRP conjugate. Validation across multiple human sample matrices confirms reliable performance for translational research, drug development screening, and population-level metabolic phenotyping projects. Single-use strip wells accommodate both small investigator-led studies and high-throughput screening campaigns.