Human Kisspeptin Receptor (KISS1R) ELISA Kit

Measuring KISS1R (also called GPR54 or AXOR12) protein in human research specimens is the purpose of this quantitative immunoassay from Assay Genie, supplied as a 96-assay microplate kit with absorbance-based readout. KISS1R is a G protein-coupled receptor central to hypothalamic-pituitary-gonadal (HPG) axis signaling, puberty onset, and reproductive hormone regulation through its role in GnRH neuron stimulation.

Validated sample matrices include tissue homogenates, cell lysates, and conditioned media from cultured cells, supporting applications in reproductive endocrinology, fertility research, idiopathic hypogonadotropic hypogonadism, and GPCR signaling studies. The plate format enables high-throughput screening, with detection performed on a standard microplate reader.

Common research uses include:

• Quantifying KISS1R expression in hypothalamic, pituitary, gonadal, or placental tissue
• Tracking receptor changes in cell-based kisspeptin signaling assays
• Investigating delayed or precocious puberty mechanisms and GnRH pulse generation
• Examining GPR54 variants and their functional impact on receptor levels

The microplate arrives pre-coated, with matched standards, detection antibody, and substrate solution provided in single-use vials. Components should be stored according to the package insert to maintain assay performance. Intended for research use only; not validated for diagnostic or clinical applications.