Human KIRREL3 PharmaGenie ELISA Kit (SBRS0807)

The Human KIRREL3 ELISA Kit from Assay Genie is part of the PharmaGenie range and is supplied on a microplate with single-use vials of capture antibody pre-coated wells, calibrator standards, and detection reagents optimized for quantification of the human KIRREL3 protein. KIRREL3 (Kin of IRRE-Like 3), also called NEPH2, is a transmembrane immunoglobulin-superfamily cell adhesion molecule that mediates homophilic binding between neurons and supports synaptic assembly, axon guidance, and the maintenance of neuronal circuitry in the developing brain. Quantifying circulating or secreted KIRREL3 supports research into neurodevelopmental disorders, with particular relevance for Jacobsen syndrome and attention deficit/hyperactivity disorder, where the gene lies within the 11q24.3 terminal deletion region on human chromosome 11. The assay is calibrated for cell culture supernatant, plasma, and serum sample matrices using a 100 uL sample volume loaded into each well, with incubation at 37 degrees C and absorbance measured on a standard plate reader. Components should be kept refrigerated between uses, protected from light, and stored sealed within the desiccant pouch to limit moisture uptake across multiple runs.