Human Kininogen PharmaGenie ELISA Kit (SBRS0814)

Quantitative measurement of human kininogen in serum samples, plasma matrices, and cell culture supernatant fractions is supported by the Assay Genie PharmaGenie ELISA platform. Kininogen is a single-chain plasma glycoprotein that serves as the precursor for bradykinin, a vasoactive nonapeptide central to the kallikrein-kinin system, vascular homeostasis, and inflammatory signaling. Tracking circulating levels of this glycoprotein aids investigations of hereditary angioedema, contact activation, and inflammatory disease pathways.

This complete microplate-format package contains pre-coated wells, detection reagents, reference standards, and substrate solution. It is validated for human-derived serum, EDTA plasma, and conditioned media from cultured cells, accommodating both clinical sample analysis and in vitro experimental workflows. Components are shipped under ambient or refrigerated conditions and should be stored according to the lot-specific certificate of analysis to preserve antibody binding activity.

Intended for research use only, the kit supports discovery applications in vascular biology, complement regulation studies, and biomarker development. To maintain assay performance, aliquot reagents upon first use, avoid repeated freeze-thaw cycles, and protect chromogenic substrate from direct light exposure.