Human Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) ELISA Kit

Quantify KIR2DS4, an activating immunoglobulin-like receptor expressed on natural killer (NK) cells and a subset of CD8+ T lymphocytes, with this ELISA kit from Assay Genie. The assay measures the human Killer-cell Immunoglobulin-like Receptor 2DS4 protein in tissue homogenates, cell lysates, and cell culture supernatants, supporting studies of innate immune regulation, NK cell receptor profiling, and ligand interactions relevant to transplant immunology and infectious disease research.

The kit is supplied in a 96-assay plate configuration, producing an absorbance signal proportional to KIR2DS4 concentration that is read on a standard microplate reader. Components include pre-coated microwell strips, detection antibody, standard, substrate solution, and wash buffer, providing sufficient reagents to complete the full plate. The protocol accommodates microliter-scale sample inputs, which is practical when working with limited patient material or primary cell lysates.

For research use only, in vitro applications include profiling NK cell receptor expression in clinical samples, screening cell lines for KIR2DS4 levels, and monitoring receptor abundance after cytokine stimulation or pharmacological treatment. Unopened kit components should be refrigerated; reconstituted standards and detection antibody benefit from freezing in single-use aliquots to limit repeated freeze-thaw cycles and preserve reagent activity.