Human KIF1B ELISA Kit (HUFI03702)

The KIF1B protein (Kinesin Family Member 1B) is a microtubule-based motor protein encoded on chromosome 1p36, with two principal isoforms (alpha and beta) generated by alternative splicing. KIF1B-alpha mediates anterograde axonal transport of synaptic vesicle precursors, while the KIF1B-beta isoform functions as a tumor suppressor implicated in neuroblastoma susceptibility and other malignancies. Loss-of-function mutations in KIF1B cause Charcot-Marie-Tooth disease type 2A1, a hereditary motor and sensory neuropathy. Researchers investigating neuronal cargo trafficking, mitochondrial dynamics, or cancer biology pathways can quantify KIF1B levels using this Assay Genie microplate kit, which supplies single-use vials, pre-coated plate strips, biotinylated detection reagent, and lyophilized standard calibrators. Store unopened components refrigerated and protect from light to preserve the shelf life of conjugate and substrate solutions.