Human KIF15 ELISA Kit (HUFI03714)

KIF15 (Kinesin Family Member 15) is a mitotic kinesin motor protein essential for bipolar spindle assembly during cell division, working in concert with KIF11/Eg5 to maintain spindle pole separation. This protein has emerged as a significant biomarker in oncology research due to its elevated expression in multiple malignancies, including breast, lung, gastric, and hepatocellular carcinomas. Dysregulation of KIF15 is associated with chromosomal instability and has been linked to resistance against Eg5 inhibitors in cancer therapy, making it an important target for both diagnostic investigations and drug development studies.

The Assay Genie Human KIF15 ELISA Kit provides researchers with a quantitative tool to measure KIF15 protein levels in human samples. KIF15 quantification aids in studies exploring mitotic regulation, cancer progression pathways, and the development of anti-mitotic therapeutic strategies. The kit supports cell biology, cancer biology, and pharmacological screening research where understanding KIF15 expression patterns contributes to broader insights into cell division mechanisms and disease states.

Intended for in vitro research use only, the kit is supplied in a pack of 96 assays and includes all reagents necessary for the ELISA procedure. Applications include investigation of KIF15 as a potential prognostic marker, evaluation of compounds targeting mitotic machinery, and characterization of KIF15 expression in tumor versus normal tissue comparisons.