Human Keratin, type II cytoskeletal 2 epidermal (KRT2) ELISA Kit

From Assay Genie, this sandwich-format ELISA kit is intended for the quantitative measurement of human Keratin, type II cytoskeletal 2 epidermal (KRT2) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids, using a colorimetric detection method. The kit reports a detection range of 0.156-10ng/mL, a sensitivity of 0.056ng/mL, an intra-assay CV of 5.2% and an inter-assay CV of 9.7%.

According to the manufacturer, KRT2 is a type II cytoskeletal keratin that is a key component of the cytoskeleton in epithelial cells, contributing to the structural integrity and function of the skin. It is described as probably contributing to terminal cornification and being associated with keratinocyte activation, proliferation and keratinization. The assay is specific to natural and recombinant human KRT2 and is intended for research use only, supporting studies in skin biology and disease pathology, including investigations of abnormalities in KRT2 expression that have been linked to various skin disorders.

Synonyms listed for the target include Cytokeratin-2e, Epithelial keratin-2e, Keratin-2 epidermis, Keratin-2e, Type-II keratin Kb2, CK-2e, K2e, KRT2A and KRT2E.