Human Kelch Like ECH Associated Protein 1 (KEAP1) ELISA Kit

Oxidative-stress research and studies of the NRF2 signaling axis require accurate measurement of KEAP1, the principal cytoplasmic repressor of NRF2 and a master sensor of electrophilic stress. This colorimetric ELISA kit from Assay Genie is calibrated for quantitative detection of human KEAP1 protein and supports investigations into redox homeostasis, KEAP1/NRF2/ARE-driven transcription, and KEAP1 loss-of-function mutations frequently observed in non-small cell lung carcinoma.

The plate-based colorimetric readout is compatible with standard benchtop microplate readers and accommodates a range of human-derived sample matrices, including blood-fraction preparations such as serum or plasma, along with tissue homogenate preparations. Researchers investigating hepatocellular responses, pulmonary inflammation, or chemoresistance mechanisms can use the kit for both mechanistic biochemistry and translational biomarker discovery workflows.

Applications include validation of KEAP1 status alongside downstream NRF2 target genes such as NQO1 and HMOX1, screening of electrophilic compounds that modify KEAP1 cysteine residues, and biomarker discovery in oncology research. The kit is supplied as a complete set of reagents with standards and detection antibody, supporting reproducible quantification across patient cohorts and matched controls in cancer biology and oxidative-stress studies.