Human KCTD13 (BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1) ELISA KIT (HUFI04952)

KCTD13 functions within the CUL3-RhoA degradation pathway, recruiting substrates for ubiquitination through its BTB/POZ adaptor domain. The protein is encoded within the 16p11.2 chromosomal region, a locus strongly linked to autism spectrum disorder, intellectual disability, and head-size variation in humans.

Researchers investigating copy-number variants at this locus use quantitative protein detection to correlate KCTD13 expression with neurodevelopmental phenotypes, neuronal migration, and synaptic architecture. The human-specific capture antibody targets endogenous protein in clinical research samples.

Store the microplate sealed at 4°C and equilibrate reagents to room temperature before each run. Provided by Assay Genie as a research-use-only immunoassay reagent for biomarker discovery in neurodevelopmental studies.