Human Jagged 2 Protein (JAG2) ELISA Kit

Jagged 2 (JAG2) is a transmembrane ligand of the Notch receptor family and plays a central role in mediating cell-cell communication during hematopoiesis, immune cell maturation, osteoblast differentiation, and epithelial-mesenchymal signaling. Quantitative measurement of circulating or tissue-derived JAG2 levels supports research into Notch pathway dysregulation, angiogenesis, and certain leukemia and solid tumor models where aberrant ligand expression has been implicated.

The Assay Genie Human Jagged 2 ELISA Kit is configured as a quantitative immunoassay intended for research use only. Each kit supplies reagents sufficient for 96 individual reactions in a microplate format, with an absorbance-based read-out suitable for standard laboratory spectrophotometers. The assay is validated for use with human samples including serum-type and plasma-type specimens, cell culture supernatants, and other relevant biological matrices, enabling studies in patient cohorts, primary cell models, and conditioned media experiments.

Researchers apply this kit to investigate Notch ligand shedding and soluble JAG2 fragments, monitor changes in ligand abundance following pharmacological intervention, and compare expression across healthy versus disease states. The accompanying protocol supports straightforward workflow integration alongside other ELISA-based biomarker panels, helping laboratories build multi-analyte profiles around Notch signaling biology.