Human IRAK3 ELISA Kit

Manufactured by Assay Genie, this sandwich ELISA kit enables the quantitative measurement of human IRAK3 (interleukin-1 receptor-associated kinase 3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It uses a colorimetric detection method and is reactive with human samples, making it a useful tool for immunology research. The kit's stated function is to inhibit dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Reported performance characteristics include a detection range of 78-5000pg/mL, a sensitivity of 20pg/mL, an intra-assay CV of 4.1%, and an inter-assay CV of 7.3%. Recovery in serum averages 103% (range 97-109%) and in plasma averages 105% (range 99-111%). The kit shows specificity for natural and recombinant human interleukin-1 receptor-associated kinase 3 and is intended for research use only.