Human IRAK1 ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the accurate measurement of human IRAK1 (Interleukin-1 receptor-associated kinase 1) levels in human samples. The kit uses a colorimetric detection method and is validated for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with specificity for natural and recombinant human Interleukin-1 receptor-associated kinase 1.

Performance data from the manufacturer report a detection range of 0.156-10ng/mL and a sensitivity of 0.078ng/mL. Precision values are stated as an Intra CV of 4.8% and an Inter CV of 8.3%, with average recovery of 98% for serum (range 92-104%) and 100% for plasma (range 94-106%).

IRAK1 is a serine/threonine-protein kinase that plays a critical role in initiating the innate immune response against foreign pathogens and is involved in Toll-like receptor (TLR) and IL-1R signaling pathways, being rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. The kit is intended for research use only and is suited to immunology research applications.