Human Interstitial collagenase (MMP1) ELISA Kit

Designed by Assay Genie for the precise measurement of human interstitial collagenase (MMP1) in biological samples, this sandwich ELISA kit supports research into collagen breakdown in the extracellular matrix. MMP1 is a key enzyme in tissue remodeling, wound healing, and disease progression, with abnormal levels linked to arthritis, fibrosis, and cancer, making it a valuable biomarker for studying these conditions. The kit shows reactivity with human samples and accepts serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, with specificity for natural and recombinant human interstitial collagenase.

The assay delivers a detection range of 0.156-10ng/mL and a sensitivity of 0.039ng/mL. Precision is reported with an intra-assay CV of 7.9% and an inter-assay CV of 11.2%. Linearity is documented for serum, EDTA plasma, and heparin plasma at dilutions of 1:2, 1:4, 1:8, and 1:16, and recovery averages 98% (range 92-104) for serum and 100% (range 94-106) for plasma. The product is for research use only and is associated with UniProt entry P03956, with the MMP1 protein functioning in collagen catabolic processes and located in the secreted extracellular space and matrix. Research area highlighted by the manufacturer is cancer.