Human Internexin Neuronal Intermediate Filament Protein Alpha (INa) ELISA Kit

Alpha-internexin (INA), a 66 kDa class IV neuronal intermediate filament protein, can be measured in research samples using this ELISA kit from Assay Genie. The 96-assay configuration is calibrated for human samples and validated against tissue homogenates and cell lysates, supporting quantitative studies of neuronal cytoskeletal proteins in neurobiology and disease research.

Alpha-internexin co-assembles with the neurofilament light, medium, and heavy chain subunits to form intermediate filament networks that maintain neuronal structure and axonal calibre. Altered expression has been reported in traumatic brain injury, amyotrophic lateral sclerosis, and other neurodegenerative contexts, making INA a useful biomarker for neuronal damage investigations. Sample preparation typically involves homogenization or lysis buffer extraction, and assay reagents are supplied in single-use vials intended to be kept refrigerated. The kit is for research use only and is intended to complement immunohistochemistry and western blot workflows that probe neuronal intermediate filament integrity.