Human Interleukin 5 Receptor Alpha (IL-5Ra) ELISA Kit

Quantitative analysis of the alpha chain of the human IL-5 receptor (CD125) supports research into cytokine signalling pathways central to eosinophil biology. This Assay Genie kit enables measurement of receptor levels in experimental samples relevant to asthma pathogenesis, allergic inflammation, and hypereosinophilic conditions.

The receptor alpha subunit confers high-affinity IL-5 binding on eosinophils and basophils, driving downstream effects on cell survival, proliferation, and effector function. Investigators studying eosinophilic oesophagitis, chronic rhinosinusitis with nasal polyps, and certain haematological malignancies find this marker useful for tracking receptor dynamics and pathway activation.

The kit supports 96 assays per microplate, providing medium-throughput capacity for screening clinical cohorts or experimental conditions. Reagents are calibrated for use with cell culture supernatants, tissue homogenates, and patient-derived biospecimens. Components include a precoated plate, detection antibody, and chromogenic substrate for readout on standard plate readers.

Storage conditions and equilibration steps are detailed in the enclosed protocol; bring sealed reagents to ambient temperature before opening vials. For research use only, not intended for diagnostic procedures.