Human Interleukin 1 Receptor Type I (IL-1R1) ELISA Kit

The IL-1 Receptor Type I (IL-1R1) functions as the primary signaling receptor for the pro-inflammatory cytokines IL-1α and IL-1β, driving NF-κB activation, leukocyte recruitment, and the acute-phase inflammatory response. This quantitative immunoassay from Assay Genie allows researchers to measure circulating and tissue-level IL-1R1 concentrations in human specimens, supporting studies in cytokine biology, rheumatology, autoinflammatory disease mechanisms, and therapeutic drug monitoring.

Each kit contains a pre-coated plate, lyophilized reference standard, biotinylated detection antibody, streptavidin-HRP conjugate, chromogenic substrate, stop solution, and concentrated wash buffer, with reagents sufficient for 96 individual determinations. The antibody-pair format delivers an absorbance-based signal measured on a standard microplate reader, and the assay has been validated across human serum samples, plasma samples, cell culture supernatant, and tissue homogenate preparations. Reagents should be kept refrigerated and protected from light; reconstituted standards are stored frozen until use. The product is intended for research use only and has not been validated for clinical diagnostic procedures.