Human Interleukin 1 Receptor Accessory Protein (IL-1RAP) ELISA Kit

Measuring Interleukin 1 Receptor Accessory Protein (IL-1RAP) in human research specimens, this quantitative immunoassay from Assay Genie supports studies of inflammatory signaling pathways. IL-1RAP, also called IL-1R3, functions as an essential co-receptor subunit within the IL-1 receptor family, partnering with IL-1R1, IL-33R (ST2), and IL-36R to transduce signals from multiple cytokines including IL-1, IL-33, and IL-36.

Investigators apply the kit to probe cytokine biology, innate immune regulation, and inflammatory disease mechanisms. Active research areas include autoimmune conditions, allergic inflammation, sepsis biology, and hematological malignancies, where IL-1RAP has emerged as a candidate therapeutic target, particularly in acute myeloid leukemia studies.

Each kit provides a pack of 96 assays with pre-coated microplate wells, standards, detection antibodies, and substrate reagents supplied in individual vials for a complete run. The assay accommodates serum samples, plasma preparations, and tissue homogenate materials from human sources. Store kit components refrigerated between uses to preserve activity. The assay is intended for research use only; refer to the enclosed protocol for handling, reconstitution of lyophilized components, and run parameters before performing the assay.