Human Inter Alpha-Globulin Inhibitor H3 (ITIH3) ELISA Kit

Inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) is a serine protease inhibitor belonging to the inter-alpha-trypsin inhibitor (ITI) family, where it circulates in plasma covalently linked to bikunin via a chondroitin sulfate bridge. The protein helps stabilize the extracellular matrix and contributes to acute-phase inflammatory regulation, and altered circulating ITIH3 levels have been reported in hepatocellular carcinoma cohorts, breast cancer cohorts, and hepatic fibrosis studies. Genome-wide association studies have also linked ITIH3 variants to schizophrenia susceptibility, broadening its research relevance beyond classical inflammation biology.

The Assay Genie Human ITIH3 ELISA Kit provides a quantitative immunoassay tool for measuring endogenous ITIH3 protein in research samples. The kit accepts diverse human specimen types, including plasma fractions, tissue homogenates, cell lysates, and cell culture supernatants. Reagents are supplied as a complete pack with a pre-coated microplate, lyophilized standards, detection reagents, and assay buffers, intended for research use only. The kit is configured as a microplate-based colorimetric immunoassay, and components require refrigerated storage to preserve activity. Researchers in oncology, hepatology, inflammation biology, and neuropsychiatric biomarker discovery use this kit for pathway-focused studies and validation experiments.