Human Integrin alpha-M/CD11b/MAC-1 PharmaGenie ELISA Kit (SBRS0800)

The Human Integrin alpha-M/CD11b/MAC-1 PharmaGenie ELISA Kit from Assay Genie quantifies CD11b, the alpha-M subunit of the beta-2 (CD18) integrin heterodimer also known as MAC-1 or complement receptor 3. Expressed on neutrophils, monocytes, macrophages, and NK cells, this receptor binds ICAM-1, iC3b, fibrinogen, and factor X, supporting studies of leukocyte adhesion, transmigration, phagocytosis, and complement-driven clearance.

Researchers apply this microplate kit to investigate neutrophil activation, sepsis-related immune dysfunction, autoimmune inflammation, transplant rejection, and tumor-associated myeloid infiltrates. Reconstituted standards and detection antibody are kept refrigerated at 4°C, aliquoted to limit freeze-thaw cycles, and shielded from light until use in the assay workflow.