Human Integrin alpha-IIb (ITGA2B) ELISA Kit

Assay Genie offers a high-quality Sandwich ELISA kit for the quantitative measurement of human Integrin alpha-IIb (ITGA2B). The assay uses a colorimetric detection method, is reactive with human samples, and accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Specificity covers both natural and recombinant forms of the target.

Performance specifications include a detection range of 0.156-10ng/mL and a sensitivity of 0.1ng/mL. Reproducibility is characterised by an intra-assay CV of 4.5% and an inter-assay CV of 8.8%. Linearity was validated in serum, EDTA plasma and heparin plasma at dilutions of 1:2, 1:4, 1:8 and 1:16. Recovery averaged 96% (range 90-102%) for serum and 98% (range 92-104%) for plasma.

Integrin alpha-IIb/beta-3 functions as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin, and mediates platelet aggregation following binding of soluble fibrinogen. The associated Uniprot reference is P08514 and the research area is Cancer. For research use only.