Human Integrin alpha-5 (ITGA5) ELISA Kit

Assay Genie provides this Sandwich ELISA Kit for the quantitative measurement of human Integrin alpha-5 (ITGA5) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The kit is intended for research use only and targets natural and recombinant human Integrin alpha-5.

Performance characteristics reported by the manufacturer include a detection range of 0.156-10ng/mL, a sensitivity of 0.078ng/mL, an intra-assay CV of 6.3% and an inter-assay CV of 9.1%. Reported linearity covers serum, EDTA plasma and heparin plasma across dilutions from 1:2 to 1:16, while recovery in serum is reported with an average of 86% (range 80-92%) and in plasma with an average of 88% (range 82-94%).

Integrin alpha-5 is described as a key cell adhesion molecule with a role in cell migration and invasion, and its dysregulation has been implicated in cancer, fibrosis and inflammatory disorders. Associated synonyms include CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e and FNRA, with the protein mapped to UniProt P08648.