Human Integrin Alpha 2B (ITGa2B) ELISA Kit

Quantitative measurement of Integrin Alpha 2B in human specimens is supported by this immunoassay from Assay Genie, formulated as a microplate kit with 96 assays per package. Integrin Alpha 2B (also called CD41 or GPIIb) combines with Integrin Beta 3 to form the GPIIb/IIIa complex, the dominant fibrinogen receptor on platelet surfaces and a focal point in studies of clot formation, platelet activation, and antiplatelet therapy development.

The assay accepts tissue homogenates, cell lysates, and a range of human-derived specimen matrices, making it applicable to platelet-rich preparations, cultured megakaryocyte samples, and platelet lysates from whole-blood donations. Researchers investigating Glanzmann thrombasthenia, a hereditary bleeding disorder linked to qualitative or quantitative defects in Integrin Alpha 2B, use kits of this kind to assess expression levels in patient-derived material alongside healthy controls.

Additional applications include cardiovascular disease research, evaluation of drug candidates targeting the GPIIb/IIIa pathway, and basic studies of integrin-mediated cell adhesion. The kit is intended for research use only, providing reproducible data for laboratory workflows in hematology, vascular biology, and translational medicine programs.