Human Insulin-like growth factor-binding protein 6 (IGFBP6) ELISA Kit

A high-quality Sandwich ELISA Kit from Assay Genie designed for the precise measurement of human Insulin-like growth factor-binding protein 6 (IGFBP6). The assay is validated for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with reactivity for human IGFBP6 and specificity for natural and recombinant human IGFBP6.

Detection is by ELISA with a detection range of 78-5000pg/mL and a sensitivity of 31pg/mL. Precision is reported as an intra-assay CV of 6.6% and an inter-assay CV of 10.2%. Recovery in serum averages 97% (range 91-103%) and in plasma averages 99% (range 93-105%).

IGFBP6 is a key regulator of insulin-like growth factor signaling, playing a role in cell growth, proliferation, and differentiation. IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of IGFs on cell culture, altering their interaction with cell surface receptors. The target (UniProt P24592) is a secreted species with a reported molecular weight of 25,322 Da, studied within the signal transduction research area. For research use only.