Human Insulin Like Growth Factor 2 Receptor (IGF2R) ELISA Kit

Quantitative measurement of Insulin-like Growth Factor 2 Receptor (IGF2R) in human samples is supported by this Assay Genie ELISA Kit. IGF2R is a ~274 kDa type I transmembrane glycoprotein that functions as the cation-independent mannose-6-phosphate receptor. It binds IGF2, drives trafficking of lysosomal hydrolases bearing mannose-6-phosphate tags, and influences cell proliferation, apoptosis, and genomic imprinting. Altered receptor levels have been reported in hepatocellular carcinoma, breast tumors, and gestational tissues, making the target relevant for oncology, endocrinology, and developmental biology studies.

Configured for standard microplate-based ELISA workflows, the kit supplies materials sufficient for a complete plate run. Researchers commonly pair IGF2R quantification with western blot or immunohistochemistry follow-up to confirm receptor expression and subcellular localization across preparations such as cell culture supernatant and tissue lysates.

For handling: refrigerate the kit upon arrival and keep unused components at 4°C. Allow all reagents to equilibrate to room temperature before each run. Aliquot working solutions to limit freeze-thaw cycles. Intended for research use only; not validated for diagnostic procedures.