Human Inducible T-Cell Co Stimulator (ICOS) ELISA Kit

Translational immunology labs studying costimulatory signaling on human T cells rely on this ELISA-based measurement of Inducible T-cell Co-Stimulator (ICOS), a CD28-family immunoglobulin receptor expressed on activated lymphocytes that pairs with ICOSL on the surface of antigen-presenting cells. Produced by Assay Genie, the kit ships with pre-coated wells, lyophilized standards, a labeled detection reagent, a chromogenic substrate solution, concentrated wash buffer, and stop solution sufficient to process one full 96-assay microplate. The assay is configured for human-derived specimens, including matched serum, urine, and cultured cell lysates, and is commonly deployed in vaccine response profiling, autoimmune disease biomarker discovery, and tumor-infiltrating lymphocyte investigations. Researchers frequently pair ICOS readouts from the same donor with flow cytometry phenotyping of follicular helper and regulatory T-cell populations, or with western blot confirmation during the same study window. Reconstituted reagents should be aliquoted into single-use vials to limit freeze-thaw cycles and stored as directed on the enclosed protocol; the plate and working buffers are intended for in vitro research use only. Each pack supports a complete plate per run, and the chromogenic signal is captured on a standard microplate reader found in most immunology core facilities.