Human IL23R (Interleukin-23 receptor) ELISA Kit (HUFI05135)

Assay Genie's quantitative immunoassay supports measurement of the interleukin-23 receptor in human research samples. The IL-23 receptor pairs with IL12Rβ1 to form the functional receptor for IL-23, activating JAK2 and TYK2 kinase signaling that drives Th17 lymphocyte differentiation. Quantifying IL23R levels is relevant to autoimmune and chronic inflammatory disease research, where IL23R polymorphisms such as the Arg381Gln variant have been linked in published studies to altered susceptibility to inflammatory bowel disease, psoriasis, and ankylosing spondylitis. The kit also supports investigations of therapeutic response to IL-23 pathway inhibitors including ustekinumab, guselkumab, and risankizumab.

Supplied in a 96 Assays configuration, the kit contains a pre-coated microplate, detection antibodies, standards, and buffers required to perform the in vitro assay. Researchers studying Th17 pathway biology, cytokine receptor expression, or biomarker discovery in autoimmune disease cohorts will find this tool applicable to their work. All components are intended for research use only and should be handled according to standard laboratory protocols for protein quantification assays.