Human IL21R (Interleukin-21 receptor) ELISA Kit (HUFI05133)

The Interleukin-21 receptor (IL-21R) is a transmembrane protein expressed primarily on lymphocytes, including B cells, T cells, and natural killer cells. This quantitative immunoassay from Assay Genie enables researchers to measure IL-21R levels in human specimens using a colorimetric signal, with the kit providing reagents sufficient for 96 Assays per plate.

IL-21R signals through JAK-STAT pathways and plays a pivotal role in humoral immunity, antibody class switching, and the differentiation of T helper 17 cells. Researchers studying autoimmune conditions, including lupus, rheumatoid arthritis, and inflammatory bowel disease, frequently investigate IL-21R expression as a biomarker of immune dysregulation. The assay also supports studies of B-cell lymphoma, graft-versus-host disease, and chronic lymphocytic leukemia.

Each kit includes pre-coated plates, detection antibodies, recombinant standards, and substrate buffers. The colorimetric method produces a measurable signal proportional to IL-21R concentration in each test sample. The kit is configured for 96 individual determinations, making it practical for medium-throughput immunology research projects in academic, clinical, and pharmaceutical laboratories.