Human IL-31 RA PharmaGenie ELISA Kit (SBRS0776)

Built around quantitative measurement of human interleukin-31 receptor A (IL-31 RA), this immunoassay from Assay Genie supports researchers tracking IL-31/IL-31 RA signaling in pruritus, atopic dermatitis, allergic airway inflammation, asthma, and progressive fibrotic disease. IL-31 RA pairs with oncostatin M receptor β to assemble the functional IL-31 receptor complex, transducing signals that drive itch, barrier disruption, and Th2-skewed immune responses, making accurate receptor quantification valuable for dermatology, allergy, and translational inflammation programs.

The 96-assay kit runs on a standard microplate reader with colorimetric signal read-out. Sample compatibility spans cell culture supernatant from stimulated primary cells or relevant cell lines, plasma collected in EDTA or heparin anticoagulant, and serum specimens. Each format is processed within the standard assay workflow with reagents sufficient for full standard curves alongside unknowns within one plate. The format supports dose-response experiments, cohort comparisons, time-course studies, and screening of clinical collections where IL-31 RA expression is being profiled alongside related mediators such as IL-31, IL-4, IL-13, TSLP, and oncostatin M.

Typical applications include cytokine pathway research in skin and airway models, biomarker discovery for atopic dermatitis and chronic pruritus, evaluation of anti-itch and anti-inflammatory compounds in vitro, and investigation of epithelial-mesenchymal cross-talk in fibrotic tissue settings. Each kit is configured as a ready-to-use research reagent set for immunology, dermatology, and respiratory research laboratories, with throughput sized to accommodate multi-condition experiments and replicate wells on one microplate.