Human IL-13ra2 ELISA Kit (HUEB0236)

The Assay Genie Human IL-13ra2 ELISA Kit is a sandwich ELISA intended for the quantitative measurement of human Interleukin-13 receptor subunit alpha-2 (IL13RA2), also referred to by the synonyms CD213a2, IL-13R, and interleukin-13-binding protein. The kit is for research use only and is validated for use with human serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, showing specificity for natural and recombinant human IL13RA2.

Reported performance characteristics include a detection range of 0.312-20ng/mL and a sensitivity of 0.1ng/mL. Intra-assay precision is given as 4.1% and inter-assay precision as 7.3%. Spike-and-recovery testing yielded an average recovery of 98% (range 92-104%) in serum and 100% (range 94-106%) in plasma.

IL13RA2 is a single-pass type I membrane protein (UniProt Q14627) that binds as a monomer with high affinity to interleukin-13 (IL13) but not to interleukin-4 (IL4). It has been implicated in the regulation of immune responses and inflammation, with relevance to conditions such as allergic asthma, inflammatory bowel disease, and multiple sclerosis, making it a useful biomarker for immunology research.